GLPG-0492 R enantiomer |CAS:1215085-93-0 Probechem Biochemicals

Chemical Structure : GLPG-0492 R enantiomer

GLPG-0492 R enantiomer (GLPG0492 R enantiomer)

Catalog No.: PC-45422Not For Human Use, Lab Use Only.

The R enantiomer of GLPG-0492, a non-steroidal selective androgen receptor modulator (SARM) for treatment for Duchenne muscular dystrophy (DMD).

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Biological Activity

The R enantiomer of GLPG-0492, a non-steroidal selective androgen receptor modulator (SARM) for treatment for Duchenne muscular dystrophy (DMD); shows weak potency (1.25 uM) compared with GLPG-0492.

Physicochemical Properties

M.Wt	389.328
Formula	C19H14F3N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzonitrile, 4-[(4R)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)-

References

1. Nique F, et al. J Med Chem. 2012 Oct 11;55(19):8236-47.

2. Cozzoli A, et al. Pharmacol Res. 2013 Jun;72:9-24.

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GLPG-0492 R enantiomer (GLPG0492 R enantiomer)

Biological Activity

Physicochemical Properties

References

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