GLPG3808 | PAPD5/7 inhibitor | Probechem Biochemicals

Chemical Structure : GLPG3808

GLPG3808 (GLPG-3808)

Catalog No.: PC-25974Not For Human Use, Lab Use Only.

GLPG3808 is a highly potent PAPD5/7 inhibitor as effective hepatitis B surface antigen (HBsAg) suppressor with EC50 of <1 nM, inhibits HBV infection in vitro and in vivo.

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Biological Activity

GLPG3808 is a highly potent PAPD5/7 inhibitor as effective hepatitis B surface antigen (HBsAg) suppressor with EC50 of <1 nM, inhibits HBV infection in vitro and in vivo.

Physicochemical Properties

M.Wt	475.92
Formula	C24H26ClNO7
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-9-chloro-1-cyclopropyl-8-(3-methoxypropoxy)-5-(3-methyloxetan-3-yl)-2-oxo-1,5-dihydro-2H-chromeno[4,3-b]pyridine-3-carboxylic acid

References

1. Mammoliti O, et al. J Med Chem. 2026 Jan 20. doi: 10.1021/acs.jmedchem.5c01703.

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GLPG3808 (GLPG-3808)

Biological Activity

Physicochemical Properties

References

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