GLUT4-IN-17 |CAS:1061081-61-5 Probechem Biochemicals

Chemical Structure : GLUT4-IN-17

GLUT4-IN-17

Catalog No.: PC-60884Not For Human Use, Lab Use Only.

A potent, selective glucose transporter 4 (GLUT4) inhibitor with IC450 of 10.8 uM, inhibits MM cell proliferation.

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Biological Activity

GLUT4-IN-17 is a potent, selective glucose transporter 4 (GLUT4) inhibitor with IC450 of 10.8 uM, inhibits MM cell proliferation.
GLUT4-IN-17 reduces ATB-BMPA binding to GLUT4 to a much greater extent than to GLUT1, inhibits 2-DOG uptake in GLUT4-expressing cells.

Physicochemical Properties

M.Wt	509.654
Formula	C31H35N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(3-((3-((methyl(quinolin-6-ylmethyl)amino)methyl)phenoxy)methyl)piperidin-1-yl)(1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)methanone

References

1. Mishra RK, et al. J Biol Chem. 2015 Jun 5;290(23):14441-53.

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GLUT4-IN-17

Biological Activity

Physicochemical Properties

References

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