GNE-6901 | GluN2A PAM | Probechem Biochemicals

Chemical Structure : GNE-6901

GNE-6901 (GNE6901)

Catalog No.: PC-22454Not For Human Use, Lab Use Only.

GNE-6901 is a selective GluN2A containing NMDAR positive allosteric modulator (PAM) wIth EC50 of 382 nM, binds to the GluN1/GluN2A LBD dimer interface.

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Biological Activity

GNE-6901 is a selective GluN2A containing NMDAR positive allosteric modulator (PAM) wIth EC50 of 382 nM, binds to the GluN1/GluN2A LBD dimer interface.

Physicochemical Properties

M.Wt	360.40
Formula	C18H17FN2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5H-Thiazolo[3,2-a]pyrimidin-5-one, 7-[(4-fluorophenoxy)methyl]-3-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]-2-methyl-

References

1. David H Hackos, et al. Neuropharmacology. 2017 Jan;112(Pt A):34-45.

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GNE-6901 (GNE6901)

Biological Activity

Physicochemical Properties

References

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