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GNE-8324

Chemical Structure : GNE-8324

CAS No.: 1698901-76-6

GNE-8324 (GNE8324)

Catalog No.: PC-22453Not For Human Use, Lab Use Only.

GNE-8324 is a selective GluN2A containing NMDAR positive allosteric modulator (PAM), binds to the GluN1/GluN2A LBD dimer interface.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GNE-8324 is a selective GluN2A containing NMDAR positive allosteric modulator (PAM), binds to the GluN1/GluN2A LBD dimer interface.

Physicochemical Properties

M.Wt 343.42
Formula C18H18FN3OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[[Ethyl(4-fluorophenyl)amino]methyl]-7,8-dihydro-4H,6H-cyclopenta[4,5]thiazolo[3,2-a]pyrimidin-4-one

References

1. David H Hackos, et al. Neuropharmacology. 2017 Jan;112(Pt A):34-45.

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