GNE-8324 | GluN2A PAM | Probechem Biochemicals

Chemical Structure : GNE-8324

Catalog No.: PC-22453Not For Human Use, Lab Use Only.

GNE-8324 is a selective GluN2A containing NMDAR positive allosteric modulator (PAM), binds to the GluN1/GluN2A LBD dimer interface.

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Biological Activity

GNE-8324 is a selective GluN2A containing NMDAR positive allosteric modulator (PAM), binds to the GluN1/GluN2A LBD dimer interface.

M.Wt	343.42
Formula	C18H18FN3OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-[[Ethyl(4-fluorophenyl)amino]methyl]-7,8-dihydro-4H,6H-cyclopenta[4,5]thiazolo[3,2-a]pyrimidin-4-one

1. David H Hackos, et al. Neuropharmacology. 2017 Jan;112(Pt A):34-45.