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Chemical Structure : GNX-865
Catalog No.: PC-62131Not For Human Use, Lab Use Only.
GNX-865 is a potent mitochondrial permeability transition pore (mPTP) inhibitor with EC50 of 105 uM (mitochondrial swelling).
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GNX-865 is a potent mitochondrial permeability transition pore (mPTP) inhibitor with EC50 of 105 uM (mitochondrial swelling); attenuates opening of the mPTP and limits reperfusion injury in a rabbit model of acute myocardial infarction.
| M.Wt | 303.742 | |
| Formula | C16H14ClNO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Fancelli D, et al. J Med Chem. 2014 Jun 26;57(12):5333-47.
2. Roy S, et al. ChemMedChem. 2015 Oct;10(10):1655-71.
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