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Chemical Structure : GPR120 agonist 4x
Catalog No.: PC-60167Not For Human Use, Lab Use Only.
GPR120 agonist 4x is a potent, selective, orally bioavailable GPR120 agonist with EC50 of 42 nM in calcium flux assays.
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GPR120 agonist 4x is a potent, selective, orally bioavailable GPR120 agonist with EC50 of 42 nM in calcium flux assays.
GPR120 agonist 4x exhibits no significant activity against hGPR40 (EC50>5 uM), no inhibitory activity against a broad panel of receptors and ion channels.
GPR120 agonist 4x also has an EC50 of 143 nM in β-arrestin assays.
GPR120 agonist 4x demonstrates in vivo antidiabetic activity in mice.
| M.Wt | 495.82 | |
| Formula | C20H12ClF6NO3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Zhang X, et al. ACS Med Chem Lett. 2017 Jul 27;8(9):947-952.
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