GPR183 antagonist SAE-1 | GPR183 antagonist

Chemical Structure : GPR183 antagonist SAE-1

GPR183 antagonist SAE-1 (SAE-1)

Catalog No.: PC-72118Not For Human Use, Lab Use Only.

GPR183 antagonist SAE-14 is a potent, selective GPR183 antagonist with IC50 of 8.3 nM, inhibits calcium mobilization induced by 7α,25-OHC in HL-60 cells.

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Biological Activity

GPR183 antagonist SAE-14 is a potent, selective GPR183 antagonist with IC50 of 8.3 nM, inhibits calcium mobilization induced by 7α,25-OHC in HL-60 cells.

Physicochemical Properties

M.Wt	375.425
Formula	C19H25N3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2,4-dimethyl-6-oxo-1,6-dihydropyrimidin-5-yl)-N-(1-(3,4,5-trimethoxyphenyl)ethyl)acetamide

References

1. Kathryn Braden, et al. J Pharmacol Exp Ther. 2020 Nov;375(2):367-375.

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GPR183 antagonist SAE-1 (SAE-1)

Biological Activity

Physicochemical Properties

References

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