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GPR43 agonist compound 187

Chemical Structure : GPR43 agonist compound 187

CAS No.:

GPR43 agonist compound 187

Catalog No.: PC-24795Not For Human Use, Lab Use Only.

GPR43 agonist compound 187 is a potent, selective GPR43 (FFAR2 or FFA2) agonist, induces Rho GTPase signaling to activate YAP/TAZ, causes YAP/TAZ accumulated in the nucleus in GPR43-expressing HEK293 cells in a manner dependent on Gα12/13 and Gαq/11.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GPR43 agonist compound 187 is a potent, selective GPR43 (FFAR2 or FFA2) agonist, induces Rho GTPase signaling to activate YAP/TAZ, causes YAP/TAZ accumulated in the nucleus in GPR43-expressing HEK293 cells in a manner dependent on Gα12/13 and Gαq/11.

Physicochemical Properties

M.Wt 419.48
Formula C19H22FN5O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

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