Catalog No.: PC-21713Not For Human Use, Lab Use Only.
GPX4 inhibitor A16 (GPX4-IN-9) is a potent, selective and covalent inhibitor of glutathione peroxidase 4 (GPX4), shows potent anti-proliferation activity the pancreatic cancer cell line AsPC-1 with IC50 of 22 nM.
GPX4 inhibitor A16 (GPX4-IN-9) is a potent, selective and covalent inhibitor of glutathione peroxidase 4 (GPX4), shows potent anti-proliferation activity the pancreatic cancer cell line AsPC-1 with IC50 of 22 nM.
GPX4 inhibitor A16 exhibits superior selectivity and potency compared to established representative GPX4 inhibitors, ML210 and ML162.
GPX4 inhibitor A16 exhibits excellent target selectivity and sensitivity across various pancreatic cancer cell lines.
GPX4 inhibitor A16 exerts its cell toxicity through a GPX4-targeting ferroptosis pathway.
GPX4 inhibitor A16 possesses moderate antitumor activity and demonstrates favorable safety under in vivo conditions.
