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GR-73632

Chemical Structure : GR-73632

CAS No.: 133156-06-6

GR-73632 (GR73632)

Catalog No.: PC-62976Not For Human Use, Lab Use Only.

GR-73632 is a potent and selective tachykinin NK1 receptor agonist with EC50 of 2 nM, promotes differentiation but not survival of rat chromaffin cells in vitro.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GR-73632 is a potent and selective tachykinin NK1 receptor agonist with EC50 of 2 nM, promotes differentiation but not survival of rat chromaffin cells in vitro.

Physicochemical Properties

M.Wt 766.01
Formula C40H59N7O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

FFPLM (Modifications: Phe-1 = delta-Aminovaleryl-Phe, Leu-4 = (methyl)Leu, Met-5 = C-terminal amide)

References

1. Phenna S, et al. Br J Pharmacol. 1996 Sep;119(2):315-20.

2. Sakurada C, et al. Peptides. 1999;20(2):301-4.

3. Meini S, et al. Neuropeptides. 1995 Feb;28(2):99-106.

4. Barker R, et al. Exp Brain Res. 1993;92(3):467-72.

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