Chemical Structure : GRK6 inhibitor 18
Catalog No.: PC-72421Not For Human Use, Lab Use Only.
GRK6 inhibitor 18 is a potent, and selective GRK6 inhibitor with IC50 of 8 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
GRK6 inhibitor 18 is a potent, and selective GRK6 inhibitor with IC50 of 8 nM.
GRK6 inhibitor 18 displays >1,000-fold selectivity over Aurora A, as well as high selectivity against a panel of 85 kinases.
GRK6 inhibitor 18 has potent cellular target engagement and antiproliferative activity against MM cells (IC50=0.4-0.46 uM) and is synergistic with bortezomib.
M.Wt | 438.916 | |
Formula | C22H23ClN6O2 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
|
1. David E Uehling, et al. J Med Chem. 2021 Aug 12;64(15):11129-11147.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright