Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : GS-462808
Catalog No.: PC-62718Not For Human Use, Lab Use Only.
GS-462808 is a potent Late INa current inhibitor of the cardiac Nav1.5 channel with IC50 of 1.33 uM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
GS-462808 is a potent Late INa current inhibitor of the cardiac Nav1.5 channel with IC50 of 1.33 uM.
GS-462808 has lower brain penetration and serendipitously lower activity at the brain isoforms, and improved CNS window (>20 rat and dog) relative to GS-458967.
GS-462808 shows improved anti-ischemic potency relative to ranolazine.
| M.Wt | 391.31 | |
| Formula | C17H12F3N5O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Koltun DO, et al. Bioorg Med Chem Lett. 2016 Jul 1;26(13):3207-11.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
