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GS-9822

Chemical Structure : GS-9822

CAS No.: 2219362-41-9

GS-9822 (GS9822;GS 9822)

Catalog No.: PC-63539Not For Human Use, Lab Use Only.

GS-9822 (GS9822) is a potent, non-catalytic site HIV integrase inhibitor with wild type EC50 of 3 nM, potently inhibits the LEDGF/p75-integrase interaction with IC50 of 70 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    GS-9822 (GS9822) is a potent, non-catalytic site HIV integrase inhibitor with wild type EC50 of 3 nM, potently inhibits the LEDGF/p75-integrase interaction with IC50 of 70 nM.

    Physicochemical Properties

    M.Wt 659.242
    Formula C36H39ClN4O4S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-2-(tert-butoxy)-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-3-(1-(oxetan-3-yl)piperidin-4-yl)-1H-indazol-5-yl)benzo[d]thiazol-6-yl)acetic acid

    References

    1. Bruggemans A, et al. Antimicrob Agents Chemother. 2023 May 1;65(5):e02328-20.

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