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Chemical Structure : GSK-872
CAS No.: 1346546-69-7
Catalog No.: PC-62661Not For Human Use, Lab Use Only.
GSK-872 (GSK'872) is a potent and selective RIPK3 (receptor-interacting protein kinase-3) inhibitor with IC50 of 1.3 nM, inhibits RIPK3-mediated necroptosis.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | Get quote |
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GSK-872 (GSK'872) is a potent and selective RIPK3 (receptor-interacting protein kinase-3) inhibitor with IC50 of 1.3 nM, inhibits RIPK3-mediated necroptosis.
GSK-872 interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle recycling.
GSK-872 attenuates rat nucleus pulposus (NP) cells death.
| M.Wt | 383.49 | |
| Formula | C19H17N2O2S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-5-benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine |
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1. Das A, et al. Tumour Biol. 2016 Jun;37(6):7525-34.
2. Qiu X, et al. Cell Death Dis. 2015 Aug 27;6:e1864.
3. Chen S, et al. Apoptosis. 2017 May;22(5):626-638.
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