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GSK 065

Chemical Structure : GSK 065

CAS No.: 1953156-61-0

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GSK 065 (GSK065;GSK-065)

Catalog No.: PC-61183Not For Human Use, Lab Use Only.

A novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 4.5 nM..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 4.5 nM.

Physicochemical Properties

M.Wt 346.767
Formula C17H15ClN2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-3-(5-chloro-6-(1-(pyridin-2-yl)ethoxy)benzo[d]isoxazol-3-yl)propanoic acid

References

1. Hutchinson JP, et al. Nat Commun. 2017 Jun 12;8:15827.

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