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GSK1034702

Chemical Structure : GSK1034702

CAS No.: 932373-87-0

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GSK1034702 (GSK-1034702;GSK 1034702)

Catalog No.: PC-35626Not For Human Use, Lab Use Only.

GSK1034702 (GSK-1034702) is a potent, allosteric M1 receptor agonist, inhibits binding of [3H]-NMS (0.5 nM) to M1 mAChR with pKi of 6.5.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GSK1034702 (GSK-1034702) is a potent, allosteric M1 receptor agonist, inhibits binding of [3H]-NMS (0.5 nM) to M1 mAChR with pKi of 6.5.
GSK1034702 improves memory encoding potentially by modulating hippocampal function.

Physicochemical Properties

M.Wt 333.407
Formula C18H24FN3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

7-fluoro-5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one

References

1. Nathan PJ, et al. Int J Neuropsychopharmacol. 2013 May;16(4):721-31.

2. Bradley SJ, et al. Mol Pharmacol. 2018 Jun;93(6):645-656.

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