Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-GPCR-GPR119-GSK1104252A
GSK1104252A

Chemical Structure : GSK1104252A

CAS No.: 1001397-20-1

Add to Favorites

GSK1104252A

Catalog No.: PC-24693Not For Human Use, Lab Use Only.

GSK1104252A is a potent, selective and orally bioavailable GPR119 agonist with pEC50 of 7.3 in reporter assay with the human GPR119 receptor stably expressed in CHO-K1 6CRE-luciferase cells.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GSK1104252A is a potent, selective and orally bioavailable GPR119 agonist with pEC50 of 7.3 in reporter assay with the human GPR119 receptor stably expressed in CHO-K1 6CRE-luciferase cells.
GSK1104252A induces GLP-1 secretion in GluTag cells with a pEC50 of 7.7.
GSK1104252A shows excellent pharmacokinetic properties and sufficient selectivity with in vivo in glucose homeostasis in the rodent.

Physicochemical Properties

M.Wt 478.54
Formula C22H27FN4O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-Piperidinecarboxylic acid, 4-[[7-[2-fluoro-4-(methylsulfonyl)phenyl]-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-, 1-methylethyl ester

References

1. Katamreddy SR, et al. J Med Chem. 2012 Dec 27;55(24):10972-94.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: