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Chemical Structure : GSK1264
Catalog No.: PC-49515Not For Human Use, Lab Use Only.
GSK1264 is an allosteric inhibitor of HIV-1 integrase, disrupts the interaction between HIV-1 integrase (IN) and the cellular factor LEDGF/p75 with IC50 of 8.2 nM, inhibits HIV-1 replication with IC50 of 38 nM.
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GSK1264 is an allosteric inhibitor of HIV-1 integrase, disrupts the interaction between HIV-1 integrase (IN) and the cellular factor LEDGF/p75 with IC50 of 8.2 nM, inhibits HIV-1 replication with IC50 of 38 nM.
| M.Wt | 453.51 | |
| Formula | C26H28FNO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gupta K, et al. J Biol Chem. 2014 Jul 25;289(30):20477-88.
2. Gupta K, et al. PLoS Biol. 2016 Dec 9;14(12):e1002584.
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