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GSK2983559

Chemical Structure : GSK2983559

CAS No.: 1579965-12-0

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GSK2983559 (GSK 2983559)

Catalog No.: PC-73178Not For Human Use, Lab Use Only.

GSK2983559 is a potent, selective and oral active receptor interacting protein 2 kinase (RIPK2) inhibitor with IC50 of 5-10 nM.

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25 mg $188 In stock
100 mg $388 In stock
200 mg $588 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GSK2983559 is a potent, selective and oral active receptor interacting protein 2 kinase (RIPK2) inhibitor.
GSK2983559 exhibits excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples.

Physicochemical Properties

M.Wt 538.53
Formula C21H23N4O7PS2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Pamela A Haile, et al. J Med Chem. 2019 Jul 25;62(14):6482-6494.

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