Chemical Structure : GSK2983559
CAS No.: 1579965-12-0
Catalog No.: PC-73178Not For Human Use, Lab Use Only.
GSK2983559 is a potent, selective and orally active receptor interacting protein 2 kinase (RIPK2) inhibitor with IC50 of 7 nM.
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GSK2983559 is a potent, selective and orally active receptor interacting protein 2 kinase (RIPK2) inhibitor with IC50 of 7 nM.
GSK2983559 exhibits excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples.
M.Wt | 538.53 | |
Formula | C21H23N4O7PS2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl dihydrogen phosphate |
1. Pamela A Haile, et al. J Med Chem. 2019 Jul 25;62(14):6482-6494.
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