GSK366 | KMO inhibitor | Probechem Biochemicals

Chemical Structure : GSK366

CAS No.: 1953157-39-5

Catalog No.: PC-61184Not For Human Use, Lab Use Only.

GSK366 is a novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 2.3 nM and 0.7 nM for human KMO and Pf-KMO, respectively.

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Biological Activity

GSK366 is a novel potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50 of 2.3 nM and 0.7 nM for human KMO and Pf-KMO, respectively.

M.Wt	361.782
Formula	C17H16ClN3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-3-(5-chloro-6-(1-(6-methylpyridazin-3-yl)ethoxy)benzo[d]isoxazol-3-yl)propanoic acid

1. Hutchinson JP, et al. Nat Commun. 2017 Jun 12;8:15827.