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GSK4394835A

Chemical Structure : GSK4394835A

CAS No.: 3032458-06-0

GSK4394835A (GSK4394835)

Catalog No.: PC-25896Not For Human Use, Lab Use Only.

GSK4394835A is a selective PDE3B inhibitor with pIC50 of 6.2, >20-fold selective over PDE3A.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GSK4394835A is a selective PDE3B inhibitor with pIC50 of 6.2, >20-fold selective over PDE3A.

Physicochemical Properties

M.Wt 499.33
Formula C27H26BN3O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(3-(Benzyl(methyl)carbamoyl)-5-(4,7-dimethoxyquinoline-2-carboxamido)phenyl)boronic Acid

References

1. Eaton SA, et al. J Med Chem. 2025 Dec 2. doi: 10.1021/acs.jmedchem.5c03081.

2. Rowley AM, et al. J Med Chem. 2024 Feb 8;67(3):2049-2065.

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