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Chemical Structure : GSM-776890
Catalog No.: PC-22499Not For Human Use, Lab Use Only.
UCSD-776890 (UCSD-776890) is a potent, selective γ-secretase modulator with Aβ42 IC50 of 4.2 nM, Aβ40 IC50 of 80 nM, also shows EC50 of 18 nM for potentiating Aβ38 secretion.
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UCSD-776890 (UCSD-776890) is a potent, selective γ-secretase modulator with Aβ42 IC50 of 4.2 nM, Aβ40 IC50 of 80 nM, also shows EC50 of 18 nM for potentiating Aβ38 secretion.
| M.Wt | 436.47 | |
| Formula | C23H22F2N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kevin D Rynearson, et al. J Exp Med. 2021 Apr 5;218(4):e20202560.
2. Pettersson M, et al. J Med Chem. 2024 Jun 7. doi: 10.1021/acs.jmedchem.4c00580.
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