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GSTO1-1 inhibitor C5-1

Chemical Structure : GSTO1-1 inhibitor C5-1

CAS No.: 158890-32-5

GSTO1-1 inhibitor C5-1

Catalog No.: PC-25454Not For Human Use, Lab Use Only.

GSTO1 inhibitor C5-1 is a potent, selective and covalent inhibitor of glutathione S-transferase omega 1 (GSTO1-1) with IC50 of 0.11 uM, selective over GSTO2-2, GSTA1-1 and GSTP1-1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GSTO1 inhibitor C5-1 is a potent, selective and covalent inhibitor of glutathione S-transferase omega 1 (GSTO1-1) with IC50 of 0.11 uM, selective over GSTO2-2, GSTA1-1 and GSTP1-1.

Physicochemical Properties

M.Wt 251.75
Formula C14H18ClNO
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(4-benzylpiperidin-1-yl)-2-chloroethan-1-one

References

1. Xie Y, et al. Eur J Med Chem. 2025 Aug 23;299:118072.

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