Chemical Structure : GW2580
CAS No.:
870483-87-7
GW2580
(GW-2580)
Catalog No. : PC-42737Not For Human Use, Lab Use Only.
GW2580 is a potent, selective c-Fms (CSF1R) inhibitor that completely inhibits human cFMS kinase in vitro at 60 nM.
Packing Price Stock Quantity 5 mg (Free Sample) $28 In stock 0 1 2 3 4 5 25 mg $128 In stock 0 1 2 3 4 5 50 mg $198 In stock 0 1 2 3 4 5 100 mg $328 In stock 0 1 2 3 4 5 250 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4273701
Biological Activity
GW2580 is a potent, selective c-Fms (CSF1R ) inhibitor that completely inhibits human cFMS kinase in vitro at 60 nM.
Physicochemical Properties
M.Wt
366.4137
Formula
C20H22N4O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: 17.5 mg/mL
Chemical Name/SMILES
2,4-Pyrimidinediamine, 5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-
References
1. Conway JG, et al. Proc Natl Acad Sci U S A.
2. Conway JG, et al. J Pharmacol Exp Ther
3. Priceman SJ, et al. Blood.
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