Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : GW274150
CAS No.: 210354-22-6
Catalog No.: PC-42897Not For Human Use, Lab Use Only.
GW274150 is a potent and highly selective inhibitor of iNOS with IC50 of 1.4 uM, displays >200 fold selectivity over eNOS and nNOS (IC50>100 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
GW274150 is a potent and highly selective inhibitor of iNOS with IC50 of 1.4 uM, displays >200 fold selectivity over eNOS and nNOS (IC50>100 uM).
GW274150 attenuates the degree of chronic inflammation and tissue damage associated with collagen-induced arthritis in mice.
GW274150 significantly reduces serum urea, serum creatinine, AST, and NAG, reduces experimental renal ischemia/reperfusion injury.
| M.Wt | 219.3045 | |
| Formula | C8H17N3O2S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
H2O: ≥ 62 mg/mL |
|
| Chemical Name/SMILES |
L-Homocysteine, S-[2-[(1-iminoethyl)amino]ethyl]- |
|
1. Young RJ, et al. Bioorg Med Chem Lett. 2000 Mar 20;10(6):597-600.
2. Cuzzocrea S, et al. Eur J Pharmacol. 2002 Oct 18;453(1):119-29.
3. McDonald MC, et al. J Physiol Pharmacol. 2002 Dec;53(4 Pt 1):555-69.
4. Chatterjee PK, et al. Kidney Int. 2003 Mar;63(3):853-65.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
