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Chemical Structure : GW441756
CAS No.: 504433-23-2
Catalog No.: PC-45453Not For Human Use, Lab Use Only.
GW441756 is a potent, specific TrkA inhibitor with IC50 value of 2 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg (Free Sample) | $28 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | $328 | In stock | |
| 250 mg | Get quote |
Bulk size, bulk discount!
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GW441756 is a potent, specific TrkA inhibitor with IC50 value of 2 nM.
GW441756 shows no significant inhibition on CDK2 and c-Raf1 (IC50> 7 uM).
GW441756 blockes gammaH2AX production and decreases ES cell proliferation.
| M.Wt | 275.3046 | |
| Formula | C17H13N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: < 11.2 mg/mL |
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| Chemical Name/SMILES |
2H-Pyrrolo[3,2-b]pyridin-2-one, 1,3-dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]- |
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1. Wood ER, et al. Bioorg Med Chem Lett. 2004 Feb 23;14(4):953-7.
2. Heinen TE, et al. Oncotarget. 2016 Jun 7;7(23):34860-80.
3. Jung EJ, et al. Mol Cells. 2008 Jul 31;26(1):12-7.
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