Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : GW843682X
CAS No.: 660868-91-7
Catalog No.: PC-42779Not For Human Use, Lab Use Only.
GW843682X is a potent and selective inhibitor of PLK1 (IC5=2.2 nM) and PLK3 (IC50=9 nM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $98 | In stock | |
| 25 mg | $148 | In stock | |
| 50 mg | $238 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
GW843682X is a potent and selective inhibitor of PLK1 (IC5=2.2 nM) and PLK3 (IC50=9 nM).
GW843682X displays >1,000-fold lower than cell CDK-2/cyclin A, CDK1/cyclin A and aurora A.
GW843682X induces a transient G2-M arrest, mitotic spindle defects, and a multinucleate phenotype.
| M.Wt | 477.4562 | |
| Formula | C22H18F3N3O4S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-Thiophenecarboxamide, 5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]- |
|
1. Lansing TJ, et al. Mol Cancer Ther. 2007 Feb;6(2):450-9.
2. Nihal M, et al. Cell Cycle. 2011 Apr 15;10(8):1303-11.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
