Catalog No.: PC-24642Not For Human Use, Lab Use Only.
Gabapentin is a potent, orally active P/Q type Ca2+ channel blocker, inhibits neuronal Ca2+ influx and reduction of neurotransmitter release, Gabapentin can antagonizes the interaction between thrombospondin-1 (TSP1 and its neuronal receptor alpha2delta1.
Gabapentin is a potent, orally active P/Q type Ca2+ channel blocker, inhibits neuronal Ca2+ influx and reduction of neurotransmitter release, Gabapentin can antagonizes the interaction between thrombospondin-1 (TSP-1) and its neuronal receptor alpha2delta1.
Physicochemical Properties
M.Wt
171.24
Formula
C9H17NO2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-(1-(Aminomethyl)cyclohexyl)acetic acid
References
1. Fink K, et, al. Br J Pharmacol. 2000 Jun;130(4):900-6.
2. Celikyurt IK, et, al. Neurosci Lett. 2011 Apr 1;492(2):124-8.
3. Kang S, et al. Cell Death Discov. 2018 Feb 20;4:31.
