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Gatifloxacin

Chemical Structure : Gatifloxacin

CAS No.: 112811-59-3

Gatifloxacin (AM 1155;BMS 206584-01;PD 135432;AM1155;BMS206584-01;PD135432;AM-1155;PD-135432)

Catalog No.: PC-42665Not For Human Use, Lab Use Only.

Gatifloxacin (PD 135432, AM1155) is a fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV.

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Biological Activity

Gatifloxacin (PD 135432, AM1155) is a fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV.
Gatifloxacin isplays 2- to 16-fold more active than ciprofloxacin and ofloxacin against Staphylococcus aureus with MICs of 0.1-0.78 ug/mL.

Physicochemical Properties

M.Wt 375.3941
Formula C19H22FN3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-

References

1. Hosaka M, et al. Antimicrob Agents Chemother. 1992 Oct;36(10):2108-17.

2. Tomioka H, et al. Antimicrob Agents Chemother. 1993 Jun;37(6):1259-63.

3. Wakabayashi E, et al. Antimicrob Agents Chemother. 1994 Mar;38(3):594-601.

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