Chemical Structure : Gatifloxacin
CAS No.: 112811-59-3
Catalog No.: PC-42665Not For Human Use, Lab Use Only.
Gatifloxacin (PD 135432, AM1155) is a fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV.
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|---|---|---|---|
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Gatifloxacin (PD 135432, AM1155) is a fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV.
Gatifloxacin isplays 2- to 16-fold more active than ciprofloxacin and ofloxacin against Staphylococcus aureus with MICs of 0.1-0.78 ug/mL.
| M.Wt | 375.3941 | |
| Formula | C19H22FN3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo- |
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1. Hosaka M, et al. Antimicrob Agents Chemother. 1992 Oct;36(10):2108-17.
2. Tomioka H, et al. Antimicrob Agents Chemother. 1993 Jun;37(6):1259-63.
3. Wakabayashi E, et al. Antimicrob Agents Chemother. 1994 Mar;38(3):594-601.

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