Chemical Structure : Gatifloxacin hydrochloride
CAS No.:
121577-32-0
Gatifloxacin hydrochloride
(AM 1155 hydrochloride;BMS 206584-01 hydrochloride;PD 135432 hydrochloride)
Catalog No. : PC-42666Not For Human Use, Lab Use Only.
A fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4266601
Biological Activity
A fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV; displays 2- to 16-fold more active than ciprofloxacin and ofloxacin against Staphylococcus aureus with MICs of 0.1-0.78 ug/mL.
Physicochemical Properties
M.Wt
411.855
Formula
C19H23ClFN3O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-, hydrochloride (1:1)
References
1. Hosaka M, et al. Antimicrob Agents Chemother. 1992 Oct;36(10):2108-17.
2. Tomioka H, et al. Antimicrob Agents Chemother. 1993 Jun;37(6):1259-63.
3. Wakabayashi E, et al. Antimicrob Agents Chemother. 1994 Mar;38(3):594-601.
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