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Geneticin sulfate

Chemical Structure : Geneticin sulfate

CAS No.: 108321-42-2

Geneticin sulfate (G-418 disulfate)

Catalog No.: PC-45352Not For Human Use, Lab Use Only.

Geneticin sulfate (G418, Antibiotic G-418 disulfate) is an aminoglycoside antibiotic with a structure similar to gentamicin, blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Geneticin sulfate (G418, Antibiotic G-418 disulfate) is an aminoglycoside antibiotic with a structure similar to gentamicin, blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.

Physicochemical Properties

M.Wt 692.7094
Formula C20H44N4O18S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

H2O: ≥ 30 mg/mL

Chemical Name/SMILES

D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)

References

1. Waitz JA, et al. Antimicrob Agents Chemother. 1974 Nov;6(5):579-81. 2. Wagman GH, et al. Antimicrob Agents Chemother. 1974 Aug;6(2):144-9.

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