Catalog No.: PC-22786Not For Human Use, Lab Use Only.
Giripladib (PLA-695) is a potent, specific cytoplasmic phospholipase A2 (cPLA2). PLA-695 inhibits radiation induced phosphorylation of ERK and Akt in cultured endothelial cells.
Giripladib (PLA-695) is a potent, specific cytoplasmic phospholipase A2 (cPLA2). PLA-695 inhibits radiation induced phosphorylation of ERK and Akt in cultured endothelial cells. PLA-695 in combination with irradiation prevented endothelial cell migration. PLA-695 enhanced radiation induced cell death and attenuated invasion of lung cancer cells. PLA-695 inhibited the formation of new blood vessels and angiogenesis.
