Catalog No.: PC-63516Not For Human Use, Lab Use Only.
Glabrescione B (GlaB) is a small molecule binding to Gli1 zinc finger and impairing Gli1 activity by interfering with Gli1/DNA interaction, inhibits Hh signaling by impairing Gli1 function.
Glabrescione B (GlaB) is a small molecule binding to Gli1 zinc finger and impairing Gli1 activity by interfering with Gli1/DNA interaction, inhibits Hh signaling by impairing Gli1 function.
Glabrescione B inhibits the growth of Hedgehog-dependent tumor cells in vitro and in vivo, inhibits Gli1-dependent growth of cerebellum-derived normal progenitors.
Glabrescione B inhibits the growth of Gli-dependent medulloblastoma and tumor-derived stem-like cells.
Glabrescione B inhibits the growth of Gli-dependent basal cell carcinoma in vitro and in vivo.
