Glesatinib (MGCD265) hydrochloride | AXL/c-Met inhibitor

Chemical Structure : Glesatinib hydrochloride

Catalog No.: PC-45668Not For Human Use, Lab Use Only.

Glesatinib (MGCD265) hydrochloride is a tyrosine kinase inhibitor that potently and selectively inhibits c-Met and Axl kinase.

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Biological Activity

Glesatinib (MGCD265) hydrochloride is a tyrosine kinase inhibitor that potently and selectively inhibits c-Met and Axl kinase.

M.Wt	655.1576
Formula	C31H27ClF2N5O3S2X
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: ≥ 28 mg/mL
Chemical Name/SMILES	Benzeneacetamide, 4-fluoro-N-[[[3-fluoro-4-[[2-[5-[[(2-methoxyethyl)amino]methyl]-2-pyridinyl]thieno[3,2-b]pyridin-7-yl]oxy]phenyl]amino]thioxomethyl]-, hydrochloride (1:x)

1. Morgillo F, et al. J Med Chem. 2017 Sep 14;60(17):7447-7458.