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Chemical Structure : Glibenclamide
CAS No.: 10238-21-8
Catalog No.: PC-21736Not For Human Use, Lab Use Only.
Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor, directly binds and blocks the SUR1 subunits of KATP.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $128 | In stock | |
| 500 mg | $188 | In stock | |
| 1 g | Get quote |
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Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor, directly binds and blocks the SUR1 subunits of KATP.
Glibenclamide inhibits P-glycoprotein and the cystic fibrosis transmembrane conductance regulator protein (CFTR).
Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability.
| M.Wt | 494.00 | |
| Formula | C23H28ClN3O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide |
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1. Heo R, et al. Life Sci. 2021;283:119868.
2. Fernandes MA, et al. J Biochem Mol Toxicol. 2004;18(3):162-169.
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