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Glofitamab

Chemical Structure : Glofitamab

CAS No.:

Glofitamab (Anti-human CD20 mAb, human IgG1-Kappa; RG-6026)

Catalog No.: PC-Ab1034Not For Human Use, Lab Use Only.

Glofitamab is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells a CD20/CD3 antibody (comprising two Fab regions for CD20 and one Fab region for CD3). Glofitamab redirects T cells to engage and eliminate malignant B cells..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Glofitamab is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells a CD20/CD3 antibody (comprising two Fab regions for CD20 and one Fab region for CD3). Glofitamab redirects T cells to engage and eliminate malignant B cells.

Physicochemical Properties

M.Wt
Formula Human IgG1-Kappa
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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