GluN2B antagonist 22 | GluN2B antagonist

Chemical Structure : GluN2B antagonist 22

Catalog No.: PC-26197Not For Human Use, Lab Use Only.

GluN2B antagonist 22 (MK-22) is a highly potent, GluN2B (NR2B)-selective NMDA receptor antagonist with IC50/Ki of 1.0 nM and 0.88 nM, respectively.

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Biological Activity

GluN2B antagonist 22 (MK-22) is a highly potent, GluN2B (NR2B)-selective NMDA receptor antagonist with IC50/Ki of 1.0 nM and 0.88 nM, respectively.

M.Wt	375.44
Formula	C20H21N7O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((1S,3S)-3-(3-(4-methylbenzyl)-1,2,4-oxadiazol-5-yl)cyclopentyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

1. Mark E Layton, et al. ACS Chem Neurosci. 2011 Jul 20;2(7):352-62.