Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Glufosfamide
Catalog No.: PC-61486Not For Human Use, Lab Use Only.
A conjugate of glucose and active alkylating moiety of ifosfamide with potentially enhanced selectivity for tumors that overexpress transmembrane glucose transporters.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A conjugate of glucose and active alkylating moiety of ifosfamide with potentially enhanced selectivity for tumors that overexpress transmembrane glucose transporters; has the better cell permeability than ifosfamide; Glufosfamide utilizes the normal cell glucose transport mechanism (SAAT1) for transport into the cell, enhances the activity of gemcitabine in vitro and in vivo.
Pancreatic Cancer
Phase 3 Clinical
| M.Wt | 383.16 | |
| Formula | C10H21Cl2N2O7P | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Veyhl M, et al. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2914-9.
2. Styczynski J, et al. Anticancer Res. 2002 Jan-Feb;22(1A):247-50.
3. Seker H, et al. Br J Cancer. 2000 Feb;82(3):629-34.
4. Ammons WS, et al. Neoplasia. 2007 Aug;9(8):625-33.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
