Glycopyrronium bromide |CAS:51186-83-5 Probechem Biochemicals

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Chemical Structure : Glycopyrronium bromide

Glycopyrronium bromide (CHF 5259;Glycopyrrolate)

Catalog No.: PC-61761Not For Human Use, Lab Use Only.

Glycopyrronium bromide (CHF 5259) is a peripherally-acting quaternary ammonium antimuscarinic agent with little or no central nervous system activity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Glycopyrronium bromide (CHF 5259) is a peripherally-acting quaternary ammonium antimuscarinic agent with little or no central nervous system activity; blocks muscarinic receptors (mAChRs), thus inhibiting cholinergic transmission.

Asthma

Approved

Physicochemical Properties

M.Wt	398.335
Formula	C19H28BrNO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	[(3S)-1,1-dimethylpyrrolidin-1-ium-3-yl] (2R)-2-cyclopentyl-2-hydroxy-2-phenylacetate bromide

References

1. Haddad EB, et al. Br J Pharmacol. 1999 May;127(2):413-20.

2. Gilman MJ, et al. Chest. 1990 Nov;98(5):1095-8.

3. Tzelepis G, et al. Eur Respir J. 1996 Jan;9(1):100-3.

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Glycopyrronium bromide (CHF 5259;Glycopyrrolate)

Biological Activity

Physicochemical Properties

References

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