Granotapide | MTP inhibitor | Probechem Biochemicals

Chemical Structure : Granotapide

Granotapide (JTT-130, JTT130)

Catalog No.: PC-24764Not For Human Use, Lab Use Only.

Granotapide (JTT-130) is a potent, intestine-specific, orally active inhibitor of microsomal triglyceride transfer protein (MTP), reduces absorption of cholesterol and triglycerides through inhibition of MTP.

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Biological Activity

Physicochemical Properties

M.Wt	718.73
Formula	C39H37F3N2O8
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Diethyl 2-((2-(3-(dimethylcarbamoyl)-4-(4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamido)phenyl)acetoxy)methyl)-2-phenylmalonate

References

1. Hata T, et al. J Pharmacol Exp Ther. 2011 Mar;336(3):850-6.

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Granotapide (JTT-130, JTT130)

Biological Activity

Physicochemical Properties

References

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