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Grifolic acid

Chemical Structure : Grifolic acid

CAS No.: 80557-12-6

Grifolic acid

Catalog No.: PC-25246Not For Human Use, Lab Use Only.

Grifolic acid is a small molecule agonist of free fatty acid receptor (FFAR4/GPR120), also is a dual antagonist of voltage-gated sodium NaV1.7 and CaV2.2 channels with potent antinociceptive effects.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Grifolic acid is a small molecule agonist of free fatty acid receptor (FFAR4/GPR120), also is a dual antagonist of voltage-gated sodium NaV1.7 and CaV2.2 channels with potent antinociceptive effects.

Physicochemical Properties

M.Wt 372.51
Formula C23H32O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,4-Dihydroxy-6-methyl-3-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)benzoic acid

References

1. Zhao M, et al. Br J Pharmacol. 2025 Aug 6. doi: 10.1111/bph.70165.

2. Zhao Y, et al. Mol Med Rep. 2018;17(2):3281-3287.

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