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Guangxitoxin 1E

Chemical Structure : Guangxitoxin 1E

CAS No.: 1233152-82-3

Guangxitoxin 1E

Catalog No.: PC-21704Not For Human Use, Lab Use Only.

Guangxitoxin 1E is a potent, specific inhibitor of Kv2.1 (KCNB1) and Kv2.2 with IC50 of 1-3 nM, has no significant effect on KV1.2, KV1.3, KV1.5, KV3.2 and BK potassium channels, also inactive against calcium and sodium channels CaV1.2, CaV2.2, NaV1.5, NaV1.7, NaV1.8.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Guangxitoxin 1E is a potent, specific inhibitor of Kv2.1 (KCNB1) and Kv2.2 with IC50 of 1-3 nM, has no significant effect on KV1.2, KV1.3, KV1.5, KV3.2 and BK potassium channels, also inactive against calcium and sodium channels CaV1.2, CaV2.2, NaV1.5, NaV1.7, NaV1.8.

Physicochemical Properties

M.Wt 3948.6
Formula C178H248N44O45S7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

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