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Chemical Structure : Guselkumab
CAS No.:
Catalog No.: PC-Ab1109Not For Human Use, Lab Use Only.
Guselkumab (CNTO-1959) is a fully human immunoglobulin-G1-lambda (IgG1λ) monoclonal antibody, selectively binds to the p19 subunit of IL-23 in dendritic cells and keratinocytes and blocks its interaction with the IL-23 receptor, which further prevents the release of other pro-inflammatory cytokines and chemokines via stimulation of immune cells, such as T helper 17 (Th17) cells. Guselkumab serum levels of IL-17A, IL-17F, and IL-22, inhibits the release of proinflammatory cytokines and chemokines
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $358 | In stock | |
| 5 mg | $758 | In stock | |
| 10 mg | $1280 | In stock | |
| 100 mg | Get quote |
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Guselkumab (CNTO-1959) is a fully human immunoglobulin-G1-lambda (IgG1λ) monoclonal antibody, selectively binds to the p19 subunit of IL-23 in dendritic cells and keratinocytes and blocks its interaction with the IL-23 receptor, which further prevents the release of other pro-inflammatory cytokines and chemokines via stimulation of immune cells, such as T helper 17 (Th17) cells. Guselkumab serum levels of IL-17A, IL-17F, and IL-22, inhibits the release of proinflammatory cytokines and chemokines.
| M.Wt | ||
| Formula | Human IgG1-Lambda3 | |
| Appearance | Solid | |
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| Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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