HAR-171 |CAS:1349902-37-9 Probechem Biochemicals

Chemical Structure : HAR-171

HAR-171 (HAR171)

Catalog No.: PC-62899Not For Human Use, Lab Use Only.

HAR-171 is a small molecule CD4 mimic and gp120-CD4 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 0.43 uM against YTA48P virus with no significant cytotoxicity (CC50>120 uM).

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Biological Activity

HAR-171 is a small molecule CD4 mimic and gp120-CD4 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 0.43 uM against YTA48P virus with no significant cytotoxicity (CC50>120 uM).

Physicochemical Properties

M.Wt	417.978
Formula	C23H32ClN3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N1-(4-chlorophenyl)-N2-(7-azadispiro[5.1.58.36]hexadecan-15-yl)oxalamide

References

1. Narumi T, et al. Bioorg Med Chem. 2013 May 1;21(9):2518-26.

2. Ohashi N, et al. ChemMedChem. 2016 Apr 19;11(8):940-6.

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HAR-171 (HAR171)

Biological Activity

Physicochemical Properties

References

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