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HAR-171

Chemical Structure : HAR-171

CAS No.: 1349902-37-9

HAR-171 (HAR171)

Catalog No.: PC-62899Not For Human Use, Lab Use Only.

HAR-171 is a small molecule CD4 mimic and gp120-CD4 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 0.43 uM against YTA48P virus with no significant cytotoxicity (CC50>120 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    HAR-171 is a small molecule CD4 mimic and gp120-CD4 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 0.43 uM against YTA48P virus with no significant cytotoxicity (CC50>120 uM).

    Physicochemical Properties

    M.Wt 417.978
    Formula C23H32ClN3O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N1-(4-chlorophenyl)-N2-(7-azadispiro[5.1.58.36]hexadecan-15-yl)oxalamide

    References

    1. Narumi T, et al. Bioorg Med Chem. 2013 May 1;21(9):2518-26.

    2. Ohashi N, et al. ChemMedChem. 2016 Apr 19;11(8):940-6.

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