HCAR3 agonist 5c | HCAR3 agonist | Probechem Biochemicals

Chemical Structure : HCAR3 agonist 5c

HCAR3 agonist 5c (GPR109b agonist 5c)

Catalog No.: PC-23376Not For Human Use, Lab Use Only.

HCAR3 agonist 5c (GPR109b agonist 5c) is a highly subtype-specific agonist of hydroxycarboxylic acid receptor 3 (HCAR3, GPR109B) with pEC50 of 7.53 and SPR KD of 47 nM, shows no activity against GPR109a.

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Biological Activity

Physicochemical Properties

M.Wt	224.22
Formula	C10H12N2O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(n-propyl)amino-3-nitrobenzoic acid

References

1. Skinner, P.J. et al. Bioorg. Med. Chem. Lett. 2007; 17:6619-6622

2. Ye F, et al. Cell Rep. 2024 Oct 19;43(11):114895.

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HCAR3 agonist 5c (GPR109b agonist 5c)

Biological Activity

Physicochemical Properties

References

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