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Chemical Structure : HDAC6-AR-IN-10
Catalog No.: PC-62788Not For Human Use, Lab Use Only.
HDAC6-AR-IN-10 is a potent dual HDAC6/AR inhibitor with IC50 of 35.6 nM/<30 nM, shows weak inhibition on HDAC1/2/3 (IC50>1 uM).
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HDAC6-AR-IN-10 is a potent dual HDAC6/AR inhibitor with IC50 of 35.6 nM/<30 nM, shows weak inhibition on HDAC1/2/3 (IC50>1 uM).
HDAC6-AR-IN-10 inhibits AR signaling and reduces the AR protein levels in LNCaP cells.
HDAC6-AR-IN-10 is a useful tool compound in pharmacology studies to evaluate the value of dual inhibition of AR and HDAC6.
| M.Wt | 579.571 | |
| Formula | C26H25F4N5O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jadhavar PS, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5222-5228.
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