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HDAC6 inhibitor 4e

Chemical Structure : HDAC6 inhibitor 4e

CAS No.: 1648893-34-8

HDAC6 inhibitor 4e

Catalog No.: PC-27053Not For Human Use, Lab Use Only.

HDAC6 inhibitor 4e is a potent, isoform-selective HDAC6 inhibitor with IC50 of 1.7 nM, shows 355-fold selectivity over HDAC1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

HDAC6 inhibitor 4e is a potent, isoform-selective HDAC6 inhibitor with IC50 of 1.7 nM, shows 355-fold selectivity over HDAC1.

Physicochemical Properties

M.Wt 384.48
Formula C21H28N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((1-butyl-3-(3-(dimethylamino)phenyl)ureido)methyl)-N-hydroxybenzamide

References

1. Tavares MT, et al. ACS Med Chem Lett. 2017 Sep 5;8(10):1031-1036.

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