HDAC6 inhibitor 7b

Chemical Structure : HDAC6 inhibitor 7b

Catalog No.: PC-27055Not For Human Use, Lab Use Only.

HDAC6 inhibitor 7d is a potent, isoform-selective HDAC6 inhibitor with IC50 of 0.87 nM, shows >500- and >3000-fold selectivity over HDAC8 and HDAC1 respectively.

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Biological Activity

HDAC6 inhibitor 7d is a potent, isoform-selective HDAC6 inhibitor with IC50 of 0.87 nM, shows >500- and >3000-fold selectivity over HDAC8 and HDAC1 respectively.

Physicochemical Properties

M.Wt	357.41
Formula	C19H23N3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-Hydroxy-4-[[1-(4-hydroxybutyl)-3-phenylureido]methyl]benzamide

References

1. Tavares MT, et al. ACS Med Chem Lett. 2017 Sep 5;8(10):1031-1036.

2. Losson H, et al. Pharmacol Res. 2020 Oct;160:105058.

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