HDAC6 inhibitor NCT-14b |CAS: 956154-63-5 Probechem Biochemicals

Chemical Structure : HDAC6 inhibitor NCT-14b

Catalog No.: PC-60830Not For Human Use, Lab Use Only.

HDAC6 inhibitor NCT-14b is a potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.

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Biological Activity

HDAC6 inhibitor NCT-14b is a potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.

M.Wt	480.71
Formula	C26H44N2O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-S-(7-(adamantan-1-ylamino)-6-((tert-butoxycarbonyl)amino)-7-oxoheptyl) 2-methylpropanethioate

1. Matsuba S, et al. J Pharmacol Exp Ther. 2014 Dec;351(3):510-8.

2. Itoh Y, et al. J Med Chem. 2007 Nov 1;50(22):5425-38.